Vol. 04 · Issue 26 Trade Briefing Buyer-Restricted 28 · 04 · 2026
A Briefing for Category Buyers

Eight active ingredients. One liquid bottle.
A fully disclosed liquid joint formula for your shelf.

Super Collagen 22oz lists eight active ingredients and their amounts in a liquid format. Review the current label, directions, warnings, wholesale terms, and available product documentation before opening an account.

Open Wholesale Account See the Margin Math Sell sheet · product documents on request when available
Account · Snapshot Terms confirmed by quote
Current Retail Price
Check
Confirm current pricing before order
Wholesale Terms
Quote
Supplied in writing per account
Product Documents
Ask
Availability varies by SKU and lot
Opening Order
Confirm
Case pack and MOQ shown in quote
Payment terms subject to approval Freight and lead time quoted per order
Nutra Botanics · Joint Plus
Super
CollagenLiquid Hydrolyzed Peptides
6,000 mg Per Serving · 32 Servings
22 fl oz · Tropical · Stevia
Active Ingredients 8 disclosed
Pathways Engaged 4 of 4
Sweetener Stevia · 0g sugar
Super Collagen Joint Plus · 22 fl oz SKU · NB-SC22-LIQ-TRO  ·  Case 12
Section01
The Numbers, First

Buyers don't decide on a story. They decide on the math.

Use the calculator below only as an illustrative scenario. Current wholesale price, retail price, case pack, freight, payment terms, and availability must be confirmed in a written quote.

Units per caseOne bottle = one consumer · 4-week supply
12
Example wholesale / unitIllustrative input, not a quote
$22.50
Example retail / unitIllustrative input; check current price
$44.99
Cases / order6 cases
Order subtotal Per opening or re-order
$1,620.00
Retail value at sell-through
$3,239.28
Gross profit (you keep)
$1,619.28
Effective margin
50.0%

Illustrative arithmetic only. It excludes freight, taxes, fees, discounts, returns, spoilage, and sell-through risk. Obtain current written terms before making a purchasing decision.

Inputs to validate for your own store.

Current category mix
Review
Shelf placement
Plan
Staff education
Plan
Expected demand
Model
Pilot order results
Measure

No sales-velocity, reorder-rate, or earnings result is promised. Use your own category data and a limited pilot to evaluate demand.

Section02
The Multi-Pathway System

Joint discomfort is not one problem. Most products treat it like it is.

The diagram summarizes proposed ingredient pathways for educational comparison. It does not establish a finished-product clinical outcome or superiority over other liquid formulas.

Four-pathway joint inflammation map showing how each Super Collagen 22oz active modulates a distinct biological pathway converging on the joint. PATHWAY 01 / STRUCTURAL REBUILD PATHWAY 03 / CARTILAGE PROTECTION PATHWAY 02 / INFLAMMATION SUPPRESSION PATHWAY 04 / SYNOVIAL LUBRICATION HYDROLYZED COLLAGEN 6,000 mg · Type I+III GLUCOSAMINE 400 mg VITAMIN C 75 mg → Pro-Hyp dipeptide signal → GAG / proteoglycan precursor → Fibroblast collagen-synthesis cofactor TURMERIC EXTRACT 200 mg · 95% curcuminoids ↓ NF-κB activation ↓ COX-2 · ↓ TNF-α · ↓ IL-6 Cytokine cascade ↓ Master inflammation switch Downstream signaling silenced CHONDROITIN SULFATE 300 mg ↓ MMP-1 · MMP-3 · MMP-13 ↓ Catabolic enzyme activity → Matrix-degrading enzyme block → Cartilage matrix preserved → Curcumin · vitamin C synergy HYALURONIC ACID 100 mg OPTI-MSM 300 mg BIOTIN 15 mcg Synovial fluid viscosity ↑ Sulfur donor · waste clearance Connective-tissue cofactor Joint Function CONVERGED OUTCOME DIAGRAM IS ILLUSTRATIVE OF PEER-REVIEWED PATHWAY LITERATURE · NOT A PRODUCT CLAIM
PATHWAY 01 Structural Rebuild

Feed the matrix the building blocks it's running out of.

Hydrolyzed peptides deliver glycine, proline, hydroxyproline — and Pro-Hyp dipeptides that signal chondrocytes to up-regulate cartilage matrix synthesis.

Actives: Collagen 6,000 mg · Glucosamine 400 mg · Vitamin C 75 mg
PATHWAY 02 Inflammation Suppression

Quiet the cytokine cascade at the master switch.

Curcumin's NF-κB inhibition is one of the most-studied anti-inflammatory pathways in the literature — downstream TNF-α, IL-6, and COX-2 signaling all attenuate.

Actives: Turmeric 200 mg (95% curcuminoids)
PATHWAY 03 Cartilage Protection

Block the enzymes that chew through cartilage.

Matrix metalloproteinases (MMP-1, -3, -13) drive cartilage breakdown. Chondroitin and curcuminoid co-action down-regulate this catabolic enzyme family.

Actives: Chondroitin 300 mg · Turmeric synergy · Vitamin C
PATHWAY 04 Synovial Lubrication

Restore the fluid the joint glides on.

Hyaluronic acid is the structural lubricant of synovial fluid. MSM contributes the sulfur every connective-tissue protein needs, and clears metabolic waste from the joint capsule.

Actives: HA 100 mg · MSM 300 mg · Biotin 15 mcg
Section03
Every Active. Every Dose. Every Pathway.

The label your buyer-rep actually wants to read.

Eight active ingredients. Zero proprietary blends. Every milligram disclosed in the rear panel — the same data the formulator works from is the same data the educator stocks the shelf with.

Ingredient
Per Serving
Pathway
Mechanism (peer-reviewed)
Reference Class
Hydrolyzed CollagenType I + Type III · Bovine
6,000mg
P1 · Structural
Pro-Hyp dipeptide signaling stimulates chondrocyte synthesis of cartilage extracellular matrix; provides amino-acid substrate for fibroblast collagen production.
PMC10058045 · J. Joint Diseases 2025 · meta-analysis JOSR 2023
Glucosamine SulfateMarine-derived crystalline
400mg
P1 · Structural P4 · Lubrication
Direct precursor for glycosaminoglycan (GAG) and proteoglycan biosynthesis; stimulates synoviocytes to secrete hyaluronic acid into the synovial fluid.
Reviewed in published joint-supplement composition literature, 2023–2026.
Chondroitin SulfateUSP-grade
300mg
P3 · Protection
Down-regulates catabolic matrix metalloproteinase activity in cartilage tissue; complementary to glucosamine in matrix preservation.
PMC peer-reviewed reviews of chondroprotective agents.
OptiMSM®Distilled methylsulfonylmethane
300mg
P4 · Lubrication
Bioavailable sulfur donor for connective-tissue proteins; supports clearance of metabolic by-products from the joint capsule, enhancing glucosamine cellular uptake.
OptiMSM® branded ingredient · published bioavailability studies.
Turmeric Extract95% curcuminoids · standardized
200mg
P2 · Inflammation P3 · Protection
Inhibits NF-κB activation upstream of TNF-α, IL-6, and COX-2; suppresses MMP-1, MMP-3, MMP-13 expression in chondrocytes.
Extensively reviewed curcumin pathway literature, 2018–2026.
Hyaluronic AcidSodium hyaluronate
100mg
P4 · Lubrication
Structural lubricant of synovial fluid; supports joint-space hydration and viscosity, reducing physical friction during articulation.
Peer-reviewed connective-tissue hydration literature.
Vitamin CAscorbic acid · 83% DV
75mg
P1 · Structural P3 · Protection
Required cofactor for fibroblast collagen synthesis (proline / lysine hydroxylation); modulates NF-κB activity and reduces MMP-3 in chondrocytes.
Established biochemical literature · vitamin C–collagen pathway.
BiotinVitamin B7 · 50% DV
15mcg
P4 · Lubrication
Co-factor in keratin and connective-tissue metabolism; complements collagen-led hair, skin, and nail support common to liquid joint shoppers.
Published B7 metabolism literature.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Section04
Format Math

Three formats, different routines.

Capsules, powders, and liquids create different preparation and shelf-placement considerations. The comparisons below are qualitative prompts; validate demand and adherence with your own customers and store data.

Format · Capsule

Capsules
& tablets

Daily pill burden4–8 caps
Dose vs. labelFollow directions
Avg compliance @ 30dValidate locally
Re-order @ 90dValidate locally
Pill count can affect preference, but no adherence or reorder outcome is assumed.
Format · Powder

Powder
tubs

Daily prepScoop + mix
Dose vs. labelNot claimed
Avg compliance @ 30dValidate locally
Re-order @ 90dValidate locally
Powders require mixing; no adherence or reorder outcome is assumed.
Format · Liquid

Super Collagen
22 oz Liquid

Daily prep1 fl oz · cap-pour
Dose vs. labelFollow directions
Avg compliance @ 30dValidate locally
Re-order @ 90dValidate locally
The liquid format avoids mixing, but no compliance or reorder result is promised. Evaluate performance with your own pilot data.

Format comparisons are qualitative planning prompts, not measured sales, compliance, or reorder claims. Validate assumptions against current written terms and your own store data.

Section05
Category Gap Analysis

A framework for reviewing your local joint-supplement set.

← Single-action Multi-pathway →
Mass-Market →
↑ Premium-Liquid
Drugstore caps
Glucosamine + chondroitin caps
Powder collagen tubs
DTC liquid (1 active)
Premium curcumin shots
Super Collagen 22oz

Buyers ask: "where could this fit?"
Your current assortment provides the answer.

The diagram is an illustrative positioning exercise, not audited market-share or competitor data. Map your actual assortment by format, ingredient count, price, customer demand, and purchase terms before deciding whether a gap exists.

  • Check 1Identify which liquid joint products and price points are already on your shelf.
  • Check 2Compare disclosed ingredient amounts, serving sizes, directions, and warnings.
  • Check 3Model margin only from current written costs and your own expected demand.
  • Check 4Use a limited pilot and your POS data to measure actual sell-through and reorder behavior.
Section06
Trust Stack

Risk-removal, line by line.

Buyers don't reject products that fail. Buyers reject products that introduce uncertainty. Below: the six categories of risk a category manager evaluates before authorizing a new line — and exactly how this brand answers each one.

01 / Compliance

Review the current label and claim language.

Confirm that the actual package, sell sheet, digital copy, warnings, and disclaimer are consistent before using the materials in your channel.

Category — Regulatory
02 / Transparency

Eight actives, every milligram disclosed.

Ingredient amounts are shown on the label. Compare any separate specification or sell sheet with the current package before relying on it.

Category — Formulation
03 / Manufacturing

Request product-specific documentation.

Ask what current manufacturing or testing documentation is available for the specific SKU and lot. Confirm the issuer, date, scope, analytes, and result before relying on a certification or batch claim.

Category — Supply
04 / Reliability

Confirm logistics in the written quote.

Lead time, stock status, freight, case pack, minimum order, and recurring-order options can change. Confirm each term before placing an order.

Category — Logistics
05 / Consumer Trust

Published consumer return window.

Eligible opened and unopened direct purchases may be returned within 90 days of delivery under the published return policy. Wholesale and retailer return terms must be confirmed separately in writing.

Category — Returns
06 / Channel Discipline

Pricing terms supplied in writing.

Ask for the current wholesale price, suggested retail price, promotion rules, marketplace policy, and channel terms before opening an account.

Category — Pricing
Section07
Sell-Through Support

Discuss the support your account needs.

Retail materials and services may change. Ask which sell sheets, shelf materials, training resources, sampling options, contacts, or marketing programs are currently available for your account.

Planogram & shelf-talker kit

Ask whether current planogram suggestions, shelf talkers, channel-strip pricing cards, or other point-of-sale materials are available.

Availability confirmed during account review

Staff training video (12 min)

Ask whether current staff-training materials are available and review all educational claims before use.

Format and availability may vary

Demo-day kit (sampling)

Ask whether sampling materials or demo support are currently offered and what account, handling, and scheduling terms apply.

Availability and terms confirmed in writing

Consumer-facing micro-site QR

Ask whether current digital education or QR-linked materials are available, then review the destination and claims before display.

Verify the live destination before use

Direct broker access

Use the trade email for current account support and ask what contact path and response expectations apply.

Contact arrangements confirmed per account

Marketing support

Ask whether a current co-op or marketing-support program is available and request its eligibility, approval, reimbursement, and use terms in writing.

No rebate or credit is promised on this page
Section08
Open the Account

One form. A documented review. Current terms before you order.

Tell us about your store and where Super Collagen 22oz might fit. The trade team can provide current pricing and discuss what product or lot documentation is available; response times and document availability can vary.

Lead timeConfirmed in the current quote
MOQConfirmed in the current quote
TermsSubject to account review and approval
FreightQuoted for the specific order
DocumentsAvailability varies by SKU and lot

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